Urinary Tract Infections
Conditions
Keywords
Funguria, Epidemiology, Urinary Tract Infections
Brief summary
This investigation is a epidemiologic case-control study of the risk factors associated with nosocomial funguria (fungi in the urine).
Detailed description
A recent large multi-center national surveillance survey of almost 5000 nosocomial (hospital based) urine isolates from medical intensive care units demonstrated that fungi comprised nearly 40% of urine isolates. Little is known about distinguishing fungi that cause colonization from those causing infection. The objective of this study is to define the epidemiology of nosocomial funguria and natural history of patients that develop funguria while hospitalized. Patients who may have eligible for this study will be identified from microbiology laboratory specimens at the Harbor-UCLA Medical Center and Cedars-Sinai Medical Center.
Interventions
None listed
Sponsors
National Institute of Allergy and Infectious Diseases (NIAID)
Cedars-Sinai Medical Center
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients hospitalized at least 12 hours of any age (\< 1 day to \> 100 years of age) AND a urine or blood culture positive for fungi, OR urine culture negative for fungi (control group)
Exclusion criteria
* Patients already surveyed for funguria during current hospitalization and patients already being followed for recognized funguria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Funguria | Hospitalization day 0, 3, 7, 14, and every 7 days thereafter until hospital discharge or death |
Countries
United States
Outcome results
None listed