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The Efficacy of Nurse-driven, Protocol Guided Ventilator Weaning in a Medical-Surgical Intensive Care Unit (ICU)

The Efficacy of Nurse-driven, Protocol Guided Ventilator Weaning in a Medical-Surgical ICU

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00786617
Enrollment
202
Registered
2008-11-06
Start date
2007-12-31
Completion date
2008-06-30
Last updated
2015-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vent Weaning in Medical- Surgical ICUs

Brief summary

1. Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have a mean length of stay on ventilator at least one day shorter than patients weaned by physician-initiated, non-protocol methods 2. Mechanically ventilated patients weaned by nurse-driven ventilator weaning protocol will have al least similar Ventilator, ICU, and Hospital Length Of Stay (LOS) compared to patients weaned by physician-initiated, non-protocol method 3. Nurse-driven ventilator weaning protocol is well accepted by other services: physicians, nurses, and respiratory therapists.

Detailed description

Ventilatory support is one of the most common indications for admission to ICU (1). The duration of mechanical ventilation is associated with several serious complications, increase mortality, prolong ICU stay, and increase hospital cost (7,8). Traditionally, the process of ventilator weaning is initiated and carried out my physicians. Recently, there have been few studies that supported the utility of protocol guided weaning algorithms. Its use have been associated with earlier initiation of weaning, leading to shorter ventilator time, and a trend for shorter ICU length-of-stay and lower hospital costs (1,2,4,9) Several studies have also shown the relative safety of utilizing nursing (3) and RT staff alone or in cooperation with medical staff in the weaning of patients from mechanical ventilation (1,2,6). We recently developed a nurse-driven ventilator weaning protocol for all ICUs at St. Luke's and Roosevelt hospitals. The protocol was approved by the Critical Care Committee and is implemented as of May 2007. All ICU nurses, respiratory therapists, and ICU physicians have been educated on this protocol We plan to prospectively collect data to look at length of stay on mechanical ventilation in patients weaned by nurse-driven ventilator weaning protocol. We plan to compare such data to retrospectively collected ventilator LOS data in patients weaned by physician-initiated ventilator weaning method.

Interventions

None listed

Sponsors

St. Luke's-Roosevelt Hospital Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Receiving MV for at least 24 hours in the ICU * Meeting established protocol criteria for a vent wean trial

Exclusion criteria

* Patients in whom MV was actively withdrawn for terminal wean * Brain dead patients on MV * Age \<18 years old * Transfers from other hospitals or health care facility who were ventilator dependent

Design outcomes

Primary

MeasureTime frame
Average Length of Stay on Ventilatorup to 5 months

Secondary

MeasureTime frame
ICU mortalityup to 5 months
Hospital mortalityup to 5 months
Treatment intensity and resource allocation: Cost of ICU care per yearup to 5 months
Level of acceptance of nurse-driven vent weaning protocolup to 5 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026