Mitochondrial Disease
Conditions
Keywords
mitochondrial
Brief summary
The objective of this research protocol is to continue investigation of the nature and prevalence of mitochondria disease and to aid patients and health care providers in the understanding of these complex disorders. This research study brings together many clinical sub-specialists to address the etiology of these disorders and to develop more effective approaches for their diagnoses and more reliable prognoses.
Detailed description
The non-invasive device named Diffuse Optical Spectroscopy developed at the Beckman Laser Institute is to be used to measure various physiological parameters. Since mitochondria produce most of the energy necessary for cellular function, their efficacy is most important for systems with a high energy demand like the brain, heart, skeletal muscle, kidney, liver, and endocrine tissues. As a result, mitochondria diseases usually manifest as complex, multi-organ disorders, requiring multispecialty investigations.
Interventions
mitochondria
Sponsors
Beckman Laser Institute University of California Irvine
University of California, Irvine
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to No maximum
Healthy volunteers
No
Inclusion criteria
* Male or female all ages group with diagnosis of mitochondrial disorder
Exclusion criteria
* Subjects with visual, auditory and/or neurological problems known to result from toxic or environmental effects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of Mitochondrial diseases | Up to 12 weeks |
Countries
United States
Outcome results
None listed