Intravenous Metoprolol Versus Intravenous Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00784316

Enrollment

316

Registered

2008-11-03

Start date

2007-08-31

Completion date

2009-07-31

Last updated

2011-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, Cardiac Surgery

Keywords

Prevention

Brief summary

The aim of the study is to test the efficiency of intravenous administration of metoprolol versus intravenous administration of amiodarone in the prevention of atrial fibrillation after cardiac surgery.

Interventions

DRUGmetoprolol, amiodarone

to compare the effectiviness of intravenous administration of metoprolol and amiodarone in the prevention of atrial fibrillation after cardiac surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* elective CABG and aortic valve patients in cardiac surgery, * previous use of betablocker therapy

Exclusion criteria

* previous atrial fibrillation or flutter, * thyroid disease, * uncontrolled heart failure, * II or III degree atrioventricular block

Design outcomes

Primary

Measure	Time frame
Incidence of atrial fibrillation	48 hours

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 30, 2026