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Fit in the Aged by Professional Training

The Effect of Different Training Modalities and Vitamin D Supplementation on Functionality in Prefrail Elderly Persons

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00783159
Acronym
FiAT
Enrollment
69
Registered
2008-10-31
Start date
2008-06-30
Completion date
2010-05-31
Last updated
2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty, Sarcopenia

Keywords

Muscle power, Frailty, Exercise, Vitamin D

Brief summary

This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

Detailed description

This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested. After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

Interventions

Power training, Vitamin D substitution

PROCEDUREStrength Training

Strength training, Vitamin D substitution

OTHERControl

Vitamin D substitution, Lifestyle consultation

Sponsors

Klinikum Nürnberg
CollaboratorOTHER
Institute of Biomedicine of Aging
CollaboratorUNKNOWN
University of Erlangen-Nürnberg
CollaboratorOTHER
Institute of Sport Science and Sport
CollaboratorUNKNOWN
Robert Bosch Medical Center
CollaboratorOTHER
University of Erlangen-Nürnberg Medical School
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Prefrailty according to the frailty score of Fried

Exclusion criteria

* Sarcoidosis * Nephrolithiasis * Plasmacytoma * COPD * Inflammatory bowel disease * Rheumatoid arthritis * History of cancer * Instable heart disease * Depression (GDS\>=6) * Dementia (MMSE\<=24) * BMI\>35kg/m² * Current attendance of muscle training * Medication: immunosuppressive drugs

Design outcomes

Primary

MeasureTime frame
Short physical performance battery3 months after intervention

Secondary

MeasureTime frame
Muscle strength and muscle power3 months after intervention

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 27, 2026