Frailty, Sarcopenia
Conditions
Keywords
Muscle power, Frailty, Exercise, Vitamin D
Brief summary
This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.
Detailed description
This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested. After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.
Interventions
Power training, Vitamin D substitution
Strength training, Vitamin D substitution
Vitamin D substitution, Lifestyle consultation
Sponsors
Study design
Eligibility
Inclusion criteria
* Prefrailty according to the frailty score of Fried
Exclusion criteria
* Sarcoidosis * Nephrolithiasis * Plasmacytoma * COPD * Inflammatory bowel disease * Rheumatoid arthritis * History of cancer * Instable heart disease * Depression (GDS\>=6) * Dementia (MMSE\<=24) * BMI\>35kg/m² * Current attendance of muscle training * Medication: immunosuppressive drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short physical performance battery | 3 months after intervention |
Secondary
| Measure | Time frame |
|---|---|
| Muscle strength and muscle power | 3 months after intervention |
Countries
Germany