Postpartum Anemia and Postpartum Depression

Is Postpartum Anemia an Independent Risk Factor for Development of Postpartum Depression?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00782912

Acronym

PPADS

Enrollment

103

Registered

2008-10-31

Start date

2008-11-30

Completion date

2014-10-31

Last updated

2019-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum Depression

Keywords

postpartum anemia, postpartum depression

Brief summary

Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status. Despite common symptoms and characteristics, a link between these entities has not been adequately studied. The objective of this study is to determine whether postpartum anemia is an independent risk factor for the development of postpartum depression. This prospective cohort study will include all women delivered by elective term cesarean delivery. Hemoglobin and iron levels will be measured, standardized questionnaires for assessment of PPD, functional status and lactation will be administered before discharge and at 3 & 6 weeks post partum. Hemoglobin levels at each time point will be analyzed for correlation with depressive symptoms, functional status and lactation success.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* Women after term elective cesarean section

Exclusion criteria

* age \< 16 years, preterm (\< 37 weeks) delivery, multiple gestation, symptomatic anemia necessitating blood transfusion, significant fetal anomalies or infant not discharged with mother for other reason, preexisting severe chronic maternal illness, preexisting maternal depression and/or current use of antidepressants, other psychiatric illness (e.g. bipolar disease, schizophrenia) or preexisting hemoglobinopathy

Design outcomes

Primary

Measure	Time frame
Incidence of postpartum depression	0-6 weeks postpartum

Secondary

Measure	Time frame
Mean Edinburgh Postnatal Depression Scale results	0-6 weeks postpartum
Functional status	0-6 weeks postpartum
Lactation success	0-6 weeks postpartum

Countries

Canada

Outcome results