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Bioavailability and Dosing of a Monosaccharide Supplement in Adults

Bioavailability and Dosing of an Oral Monosaccharide Supplement in Adults and Effects on Resting Brain Activity

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00782392
Enrollment
15
Registered
2008-10-31
Start date
2007-01-31
Completion date
Unknown
Last updated
2011-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Males

Keywords

Nutrition, Infant Formula

Brief summary

We are developing an oral supplement of carbohydrates to be added to infant formulas in order to improve brain development, immune function, and overall health of infants and children. After a careful review of what is known about these sugars, there is very little information regarding their use in infants and children, although there is some information in adults and animals. Many of these sugars have been used in a glyco-nutritional supplement in adults and children, with minimal or no reported side effects. We are developing a custom blend of important individual sugars, and need information regarding their dosing and blood concentrations following oral intake of the carbohydrate supplement. Timed blood samples following the carbohydrate supplement will provide us with a better understanding of the most effective dose and the metabolism of these sugars in adults. This will give us the preliminary information we need for developing an oral supplement of special sugars that can be added to infant formulas to help improve brain development and immune function in infants and children.

Interventions

None listed

Sponsors

University of Arkansas
CollaboratorOTHER
United States Department of Agriculture (USDA)
CollaboratorFED
Arkansas Children's Hospital Research Institute
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
MALE
Age
18 Years to 28 Years
Healthy volunteers
Yes

Inclusion criteria

* Caucasian (non-hispanic) * Male * Age 18-28 * Regularly eat breakfast * Healthy * BMI within normal limits (18.5 - 24.9) * English speaking

Exclusion criteria

* History of smoking, more than occasional alcohol use, or drug use. * Chronic medical diagnosis * Medications that may interfere with the study

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026