Kidney Failure
Conditions
Keywords
Acute Kidney failure, Clinical outcomes, On-pump, Coronary artery bypass grafting, Morbidity, Mortality
Brief summary
The purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.
Detailed description
Eight hundred and seventeen patients was enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after on-pump CABG. Group AKI (+) - patients with acute kidney injury after on-pump CABG. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Clinical Outcomes and 30-day mortality was evaluate in this patients.
Interventions
None listed
Sponsors
Hospital de Base
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients underwent on-pump coronary artery bypass grafting * Patients with at least two serum creatinine values within 48 hours.
Exclusion criteria
* Patients with end-stage kidney disease requiring renal replacement therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To test the hypothesis that patients with acute kidney injury after on-pump CABG have higher 30-day mortality | 30 days |
Secondary
| Measure | Time frame |
|---|---|
| To compare clinical outcomes in patients with and without acute kidney injury after on-pump CABG | 30 days |
Outcome results
None listed