Bleeding
Conditions
Keywords
Thrombelastogram, Microvascular bleeding, antiplatelet medication, cardiac surgery, consumption of blood products, preoperative platelet mapping derived from modified TEG, postoperative bleeding
Brief summary
Study Objective is to correlate the results of preoperative platelet mapping derived from modified TEG with clinically significant postoperative bleeding and consumption of blood products.
Detailed description
Study Design: Prospective observational study with blinded assessment of study endpoint variables. Collection of information concerning study endpoints will be performed by the investigator blinded to the results of preoperative testing of platelet function. The information will be collected from 60 patients undergoing cardiac surgery in the Department of Cardiac Surgery of Sheba Medical Center. Study endpoints 1. Primary endpoint- resternotomy for bleeding after the surgery. 2. Secondary endpoints- chest tube output during first 24 hours after the surgery; consumption of blood products during first 3 postoperative days.
Interventions
None listed
Sponsors
Sheba Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing cardiac surgery with the history of aspirin and/or ADP receptor antagonist for at least 7 days prior the surgery
Exclusion criteria
* Emergent surgery * Heart transplant surgery * Implantation of ventricular assist devices * Enrollment into conflicting study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Re-sternotomy d/t Bleeding | Hospitalization Period |
Secondary
| Measure | Time frame |
|---|---|
| Chest tube output during first 24 hours after the surgery | 24 hours |
Countries
Israel
Outcome results
None listed