Skip to content

Relative Effects and Predictive Models of Contemporary Upper Limb Training Programs in Stroke Patients

Relative Effects and Predictive Models of Contemporary Upper Limb Training Programs in Stroke Patients Delivered in Hospital-based and Home-based Settings

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00778453
Enrollment
150
Registered
2008-10-23
Start date
2008-08-31
Completion date
2011-07-31
Last updated
2012-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular Accidents

Keywords

stroke rehabilitation, kinematic analysis, upper extremity training, predictors

Brief summary

The findings of this study will advance movement reorganization mechanism underlying treatment approaches and clinical intervention techniques. These findings may inform rehabilitation professionals about which treatment approach is superior to another one in certain aspect of outcome and who can benefit most from certain treatment approach. Accordingly, the results of this project may help us move quickly to design and develop efficient and effective rehabilitation programs for individualized patients.

Detailed description

The first purpose is to investigate the relative effects of modified constraint-induced therapy (mCIT) vs. bilateral isokinematic training (BIT) vs. traditional or therapist-based training (TR) on movement reorganization, motor performance, functional ability, and quality of life (QoL) immediately and six months later after treatment delivered at hospitals. Movement reorganization will be evaluated by kinematic instrument. Motor performance, functional ability, and QoL will be assessed using clinical assessment tools. By the same token, we also investigate the relative effects of these two approaches delivered at home. The second purpose is to study whether home-based mCIT is efficacious in various aspects of outcomes described above immediately and six months later following treatment, compared to home-based TR, and hospital-based mCIT and TR.We also study the same question regarding home-based BIT efficacy. The third purpose is to establish predictive models to predict functional and QoL outcomes immediately and six months later following mCIT and BIT.

Interventions

restraint of the unaffected arm and practice of the affected arm

OTHERHospital-based BIT

bilateral symmetric, repetitive arm training

hospital-based traditional rehabilitation : OT or PT or therapist-based training

OTHERHome-based mCIT

restraint of the unaffected arm and practices of the affected arm

OTHERHome-based BAT

bilateral symmetric, repetitive arm training

OTHERHome-based TR

home-based traditional rehabilitation:OT or PT or therapist-based training

Sponsors

National Science and Technology Council, Taiwan
CollaboratorOTHER_GOV
National Health Research Institutes, Taiwan
CollaboratorOTHER
Chang Gung Memorial Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
35 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* the onset duration more than 6 months * Brunnstrom stage III above for the proximal part and distal part of UL * no serious cognitive deficits * no balance problems sufficient to compromise safety when wearing the project's constraint device * no excessive spasticity in any of the joints of the affected UL

Exclusion criteria

* a score of less than 24 on the Mini Mental State Exam

Design outcomes

Primary

MeasureTime frame
kinematic analysis2008-2011

Secondary

MeasureTime frame
clinical measures2008-2011

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026