Acute Kidney Injury After Cardiac Surgery Based on KDIGO Criteria

Prognostic Value of Acute Kidney Injury After Cardiac Surgery According to Kidney Disease: Improving Global Outcomes Definition and Staging (KDIGO) Criteria

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00777465

Enrollment

2804

Registered

2008-10-22

Start date

2003-01-31

Completion date

2013-06-30

Last updated

2014-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Keywords

Acute kidney injury, Kidney failure, Risk factors, Clinical outcomes, Cardiac valve surgery, Coronary artery bypass grafting, Morbidity, Mortality

Brief summary

The aim of this study was to apply the acute kidney injury criteria based on KDIGO classification in a population of patients undergoing cardiac surgery \[coronary artery bypass grafting (CABG) or cardiac valve surgery (CVS)\] and evaluate its impact as a predictor of 30-day mortality.

Detailed description

This was a single center study. We evaluated retrospectively patients from the Cardiac Surgery Intensive Care Unit in Hospital de Base, São José do Rio Preto Medical School, São Paulo, Brazil. Demographics, type of surgery, laboratory data and preoperative, perioperative, and postoperative information were retrieved from a prospectively collected database of 2878 patients older than 18 years undergoing isolated CABG (1786) or CVS (1092), from January 2003 to June 2013. After applying the exclusion criteria (51 patients with incomplete data and 23 patients with end-stage kidney disease) we analyzed 2804 patients in total, 1738 (62%) underwent CABG and 1066 (38%) underwent CVS.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

patients undergoing isolated coronary artery bypass grafting or cardiac valve surgery.

Exclusion criteria

patients with incomplete data and patients with end-stage kidney disease.

Design outcomes

Primary

Measure	Time frame	Description
Acute Kidney Injury after cardiac surgery as a independent predictor of 30-day mortality	30 days	To test the hypothesis that the acute kidney injury based on KDIGO criteria after cardiac surgery is a independent predictor of 30-day mortality

Countries

Brazil

Outcome results