Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00777218

Enrollment

Registered

2008-10-22

Start date

2007-08-31

Completion date

2011-07-31

Last updated

2020-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Keywords

migraine

Brief summary

The purpose of this study is to determine if there are significant differences in the side effects related to memory, repetition and recall among these three drugs when used in a pediatric population.

Interventions

DRUGpropranolol

standard pediatric doses, based on body weight

DRUGzonisamide

standard pediatric dosages, based on body weight

DRUGtopiramate

standard pediatric dosages, based on body weight

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

8 Years to 17 Years

Healthy volunteers

Inclusion criteria

* diagnosis of migraine with and without aura or chronic daily headache as defined by IHS * subjects must between the age of 8-17 (inclusive)

Exclusion criteria

* diagnosis of tension-type headache or cluster headache

Design outcomes

Primary

Measure	Time frame
Record if memory, repetition or recall was impaired by subject during specific time frame on medication.	3 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026