Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00775879

Acronym

SIZE

Enrollment

Registered

2008-10-20

Start date

2006-03-01

Completion date

2008-07-01

Last updated

2026-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anesthesia

Keywords

Général anesthesia, Gynecology

Brief summary

Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.

Interventions

DRUGInduction with Sevoflurane

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* programmed gynecological surgery * ASA 1 or 2

Exclusion criteria

* arterial hypertension * gastro-oesophageal reflux * pregnancy * diabetes * obesity * asthma * tobacco

Design outcomes

Primary

Measure	Time frame
Incidence of spike wave	during anaesthesia induction with sevoflurane

Countries

France

Contacts

PRINCIPAL_INVESTIGATORBenjamin JULLIAC, Dr

University Hospital, Bordeaux

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 19, 2026