Traumatic Brain Injury
Conditions
Brief summary
This study will test if patients with moderate to severe traumatic brain injuries also have endocrine abnormalities, examine any existing relationships among fatigue, depression and endocrine abnormalities, and the relationship between endocrine abnormalities, quality of life, and community integration.
Interventions
None listed
Sponsors
Kessler Foundation
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Having moderate to severe TBI at least 3 months prior to enrollment. This can be demonstrated by a history of loss of consciousness, amnesia or another neurologic deficit after brain injury * Be between the ages of 18 and 70 years
Exclusion criteria
* History of prior TBI, stroke, seizures, severe psychiatric disturbances (i.e., those known to influence memory performance, such as schizophrenia, bipolar disorder), or drug abuse will be excluded. * Pregnant, nursing, or planning pregnancy during the study period. * Dementia * Other neurological conditions which are associated with aging and known to cause fatigue (e.g. Parkinson's Disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To further study the incidence of fatigue and endocrine abnormalities in an outpatient TBI population | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| To study the relationship between fatigue and endocrine abnormalities | 1 year |
Countries
United States
Contacts
Primary ContactAnthony Lequerica, Ph.D.
Backup ContactAlexandria Muench
Outcome results
None listed