Prostate Cancer
Conditions
Keywords
patients with cancer in the prostate
Brief summary
The optimal amount of fluid a patient need under surgery is not clear. Both to much and to little fluid can damage the organ functions. A strategy called Goal directed therapy, where the fluid amount a patient need is guided by the stroke volume, has shown to minimize post-operative nausea and vomiting. The investigators intend to investigate if patients treated after these standards, has a better outcome then patients treated after normal regimes, regarding post-operative orthostatic-intolerance.
Interventions
PROCEDUREStandard therapy
Standard therapy
PROCEDUREMaximization of cardiac stroke volume with fluid infusion
Maximization of cardiac stroke volume with fluid infusion
Sponsors
Rigshospitalet, Denmark
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with cancer in there prostate
Exclusion criteria
* Patients who don't understand the information * ASA \> III * Patients that are under treatment with the drug triazolam * Patients with af known renal decease * Patients with a psychiatric decease * Alcohol abuse * Severe haemorrhagic decease * Cancer in the mouth,pharynx, larynx or oesophagus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate | 6 hours |
Secondary
| Measure | Time frame |
|---|---|
| Investigate intraoperative haemodynamics | Intraoperative |
Countries
Denmark
Outcome results
None listed