Peripheral Metabolic Effects of Ghrelin

Peripheral Metabolic Effects of Intra Arterial Ghrelin Infusion in Healthy Controls

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00771940

Enrollment

Registered

2008-10-15

Start date

2008-10-31

Completion date

2009-01-31

Last updated

2009-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Controls

Brief summary

The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.

Interventions

DRUGGhrelin

Solvent, cont. infusion

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

1. BMI \< 27 kg/m2 2. Written informed consent 3. Non-smoker

Exclusion criteria

1. Any disease including epilepsy 2. Any use of medications (excl. paracetamol) 3. Present or previous malignancy 4. Alcohol dependency 5. Allergy to any trial medication

Design outcomes

Primary

Measure	Time frame
Plasma levels of glucose	During study day

Secondary

Measure	Time frame
Insulin signaling	Study day
Serum levels of fatty acids	Study day

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026