Phentermine/Gastric Band Weight Loss Study

Does the Addition of Phentermine Increase Weight Loss in the Obese After Gastric Band Operation?

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00771654

Enrollment

Registered

2008-10-13

Start date

2009-02-28

Completion date

2010-09-30

Last updated

2022-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

This is a prospective, randomized, double-blind controlled trial. The goal is to show whether the administration of daily oral Phentermine will augment patient weight loss and resolve obesity associated comorbidities following gastric band operation.

Interventions

DRUGPhentermine

Subjects will receive Phentermine 37.5mg everyday for one year

OTHERPlacebo

daily for one year

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult age 18-65 * BMI 35-55 * Approved for gastric band operation

Exclusion criteria

* A known allergy to Phentermine * Take medications for Attention Deficit Disorder (ADD) * Monoamine oxidase inhibitors (MAOI)for depression * Selective serotonin reuptake inhibitor (SSRIs)for depression * History of heart problems (congested heart failure, coronary artery disease,cardiac stents, cardiac arrhythmias * Hyperthyroidism * Glaucoma * Psychosis * History of drug abuse * Uncontrolled hypertension (diastolic \>85)

Design outcomes

Primary

Measure	Time frame
Primary outcomes are total weight loss and excess weight	one year

Secondary

Measure	Time frame
Secondary outcomes is resolution of preoperative comorbidities	one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026