Study Evaluating the Nasopharyngeal Carriage in Healthy Children

Nasopharyngeal Carriage in Children After Introduction of General Pneumococcal Immunization in Germany

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00768833

Acronym

Carriage

Enrollment

242

Registered

2008-10-08

Start date

2008-10-31

Completion date

2014-08-31

Last updated

2014-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Subjects

Keywords

S.pneumoniae healthy subjects, Healthy subjects

Brief summary

The purpose of this study is to assess the prevalence of pneumococcal stereotypes in the nasopharynx of healthy children and to describe the changes of nasopharyngeal carriage at different ages over time.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

3 Months to 4 Months

Healthy volunteers

Yes

Inclusion criteria

Main inclusion criteria: * Age at enrolment 3 to 4 month Main

Exclusion criteria

* Malformation or injury of the nasopharynx * Known or suspected immunodeficiency * Relevant immunosuppression * Use of antibiotics up to 10 days prior to study inclusion

Design outcomes

Primary

Measure	Time frame
Number and frequency of S. pneumonia positive serotypes	57 months

Secondary

Measure	Time frame
Changes in number and frequency of S. pneumonia positive children at different ages over time	57 month

Countries

Germany

Outcome results