Bulimia Nervosa, Eating Disorders
Conditions
Keywords
binge eating behavior, adolescents
Brief summary
This is a study of topiramate to see whether topiramate decreases binge eating behavior among adolescents and young adults. The investigators did also checked whether topiramate affected cognitive function or not.
Interventions
DRUGtopiramate
Sponsors
The Zucker Hillside Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Eligibility
Sex/Gender
ALL
Age
12 Years to 23 Years
Healthy volunteers
No
Inclusion criteria
Subjects (aged 12 to 23) were included if they * Met the criteria of bulimia nervosa or eating disorder NOS with binge-eating behavior in DSM-IV-TR, * Had weight \> or = 100th % of expected body weight for their age, * Engaged in binge eating at least once a week for 9 out of the 12 weeks prior to the study entry, and * Were judged by a clinician to be stable enough to be treated for their psychiatric condition as an outpatient (i.e, no acute suicidality, hallucination, unstable vital signs or persistently abnormal laboratory results due to eating disorder).
Exclusion criteria
* Subjects whose psychotropic medications had been changed within 4 weeks prior to the entry or who had started psychotherapy within 3 months prior to the entry were excluded. * Subjects were also excluded if they were taking carbonic anhydrase inhibitors, carbamazepine, phenytoin, phenobarbital, valproic acid, evening primrose oil or oral contraceptives. * Other
Countries
United States
Outcome results
None listed