Skip to content

Analysis of the Early Development of the Visual Function in Extreme Premature Infants Under 28th Weeks of Gestation

Analysis of the Early Development of the Visual Function in Extreme Premature Infants Under 28th Weeks of Gestation. - A Prospective Study to Identify Normal Values of Flash Visual Evoked Potentials in This Population

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00768586
Acronym
fVEP
Enrollment
40
Registered
2008-10-08
Start date
2008-02-29
Completion date
Unknown
Last updated
2008-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vision

Brief summary

The aim of this study is to collect data on the early visual development of extreme premature infants. The method is the measurement of flash visual evoked potentials and the study population includes premature infants under the 28th weeks of gestation, who have normal cranial ultrasound examinations, normal aEEG, no clinical neurological symptoms and who have a normal ophthalmological status. fVEP measurements were recorded from the first week of life every second week until term. The fVEP recordings were performed in active sleep, in stable premature infants, who were continuously monitored. The Nihon Kohden Neuropack 8 was used, the stimulus frequency was 0,5 Hz, artefact free averages were analyzed. The measurements were analyzed according to the presence and absence of known waveforms, their latencies and amplitudes. Longitudinal analysis was performed to analyse the effect of extrauterine visual development on fVEP with growing gestational ages.

Interventions

None listed

Sponsors

Medical University of Vienna
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
23 Weeks to 29 Weeks
Healthy volunteers
No

Inclusion criteria

* All premature infants under the 29th week of gestation entering our ward.

Exclusion criteria

* Infants with intracranial abnormalities, cerebral malformations, neurological symptoms or known eye pathology.

Design outcomes

Primary

MeasureTime frame
Latency and Amplitude of Visual Evoked Potential waveforms measured in the first week of life than every second week prospectively until term.Until term

Countries

Austria

Contacts

Primary ContactKatrin Klebermass, MD,
katrin.klebermasz@meduniwien.ac.at0043140400

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026