Removal of Uremic Toxins With Nocturnal Dialysis Versus Standard Dialysis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00766792

Enrollment

Registered

2008-10-06

Start date

2005-12-31

Completion date

2008-07-31

Last updated

2008-10-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Failure

Brief summary

Dialysis patients, who decide to switch from standard dialysis (3 times 240-270 min/week) to nocturnal dialysis (3 times 480 min/week), will be followed. In parallel a control group with patients staying on standard dialysis will be followed. The study will last 30 weeks. During this period blood samples (pre- and post-dialysis: 10 times; inlet and outlet of dialyzer: 3 times) will be collected on predetermined time points. Concentration of several uremic retention solutes will be determined.

Interventions

PROCEDURENocturnal dialysis

Switch to nocturnal dialysis (3 times 480 min/week)

PROCEDUREStandard dialysis

Standard dialysis (3 times 240-270 min/week)

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 years

Exclusion criteria

* pregnancy

Design outcomes

Primary

Measure	Time frame
To evaluate what is more effective for removal of uremic toxins - nocturnal versus standard dialysis?	30 weeks

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026