Postoperative Atrial Fibrillation
Conditions
Brief summary
Atrial Fibrillation (AF) is one of the most common postoperative complications after coronary artery bypass grafting (CABG). Postoperative AF produces a substantial impact on hospital resources with an estimated annual expenditure of over $1 billion. This includes the cost of pharmacological treatment and the cost of the increased length of stay. The incidence of AF is about 30-40% in CABG patients and increases with age of the patient. As the average age of the patient that undergoes CABG surgery is increasing, it is critical to find a way to prevent or reduce the incidence of this complication. We propose a prospective, randomized, controlled study to determine the role of pulmonary vein isolation by bipolar ablation in the prevention or reduction of postoperative AF. The block- randomization plan will be used to maintain balance of the study and control arms throughout the study.
Interventions
PROCEDUREIsolation of pulmonary veins with Bipolar radiofrequency ablation
Sponsors
University of Pittsburgh
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. Patients who require an isolated elective CABG surgery on CPB. 2. Both male and female patients of age 18 years to 90 years.
Exclusion criteria
1. Pre existing atrial fibrillation or history of previous atrial fibrillation. 2. Inability to provide informed consent. 3. Pregnant or nursing patients. 4. Reoperative sternotomy 5. Emergency CABG surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduced incidence of Postoperative Atrial fibrillation | 12 hours |
Countries
United States
Outcome results
None listed