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The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization

a Non-invasive Device for the Detection, Diagnosis and Screening of Oral Pathology

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00764569
Enrollment
77
Registered
2008-10-02
Start date
2008-11-30
Completion date
2011-06-30
Last updated
2022-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other Lesions of Oral Mucosa

Keywords

oral tissue

Brief summary

The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.

Detailed description

Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.

Interventions

DEVICEFluorescence/Elastic Scattering Spectroscopy

Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Sponsors

Beckman Laser Institute University of California Irvine
CollaboratorOTHER
University of California, Irvine
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* adult over 18 years of age

Exclusion criteria

* younger than 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Diagnostic Tool4 weeksFluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026