Tumor Growth Factors in Hepatocellular Carcinoma

Insulin-like Growth Factors (IGF) Axis (IGFs, Its Binding Proteins,Receptors), Transforming Growth Factor Alpha and Beta 1 and Epidermal Growth Factor in the Urine and Serum of Patients With Hepatocellular Carcinoma.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00764140

Enrollment

400

Registered

2008-10-01

Start date

2007-01-31

Completion date

2010-04-30

Last updated

2013-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Keywords

tumor growth factor

Brief summary

Malignant cells frequently produce many tumor growth factors to autocidal or endocrinal proliferate growth, metastasis,or angiogenesis about tumor cells. By studying tumor growth factors in hepatocellular carcinoma, one may know the tumor behavior, its relationship with clinical manifestation or invasion, and could be used as diagnostic or prognostic tools.This study aims to study the relationship between tumor growth factors in HCC ant its clinical relevance.

Detailed description

The clinical relevance of patients will be evaluated by the concentrations of tumor growth factors.

Interventions

BIOLOGICALtumor growth factor concentration

spot urine or blood collection will be used to measure specific tumor growth factor

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Histology proven HCC

Exclusion criteria

* No definitely diagnosed tumor

Design outcomes

Primary

Measure	Time frame
mortality	5 years

Secondary

Measure	Time frame
distant metastasis	5 years

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026