Postmenopausal Women, Stable Angina Pectoris
Conditions
Keywords
Coronary Artery Disease, ischemia diagnostic
Brief summary
Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.
Detailed description
In order to investigate which ischemia diagnostic presents which sensitivity and specificity for postmenopausal women, 100 consecutive patients presenting to our abmulance with stable angina pectoris and indication for myocardial szintigraphy will be enrolled in this study. An addidional stress-echocardiography and stress-MRI will be performed in this patients before they will reiceve their again routine coronay angiography. The different methods for ischemia diagnostic will be compared in order to determine the most valid method for this specific population.
Interventions
PROCEDUREstress-echocardiography
stress-echocardiography will be performed once using Adenosin (140 µg/kg/min over 6 Minutes) and a contrast agent (SonoVue)
PROCEDUREstress-MRI
stress-MRI will be performed once using Adenosin (140 µg/kg/min over 6 Minutes)and a contrast agent (Gadovist)
Sponsors
RWTH Aachen University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Postmenopausal women presenting to the hospital with stable Angina pectoris complaints and an indication for myocardial szintigraphy
Exclusion criteria
* CABG * Pacemaker or other metal implants * Chronic bronchitis * Asthma bronchiale * Arterial Hypotension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparision of different ischemia diagnostic methods | before routine coronary angiography |
Countries
Germany
Outcome results
None listed