Periodontal Disease and Cardiovascular Disease

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00763165

Enrollment

438

Registered

2008-09-30

Start date

2000-11-30

Completion date

2009-12-31

Last updated

2008-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases

Brief summary

To access the influence of triclosan dentifrice on the progression of periodontal disease in patients with coronary heart disease.

Interventions

DRUGTriclosan

Brush twice daily

DRUGFluoride

Brush twice daily

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* A minimum of 12 uncrowned teeth other than 3rd molars * Age 18 to 75 years * Informed consent

Exclusion criteria

* Prosthetic heart valves * Prosthetic joint replacement * Previous infective endocarditis * Requirement for antibiotic cover for dental treatment * Current treatment with warfarin

Design outcomes

Primary

Measure	Time frame
Periodontal disease	3-5 Years

Countries

Australia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026