Insulin Sensitivity, Type 2 Diabetes
Conditions
Keywords
Intra-Abdominal Fat, Adipokines, Exercise, Diet therapy
Brief summary
The purpose of this study was to evaluate the effects of 12 weeks' increased daily physical activity versus diet restriction on regional fat distribution, insulin sensitivity and adipokines including retinol binding protein-4 (RBP-4), leptin, adiponectin, and a new marker, adiponectin to leptin ratio (AL ratio), in type 2 diabetic women.
Interventions
BEHAVIORALStandard life style modification for type 2 diabetes
Two session of education for exercise and diet. \----------- Exercise: 30min/day x 4/week Diet: ideal body weight x 30\ 35kcal/day
BEHAVIORALDiet restriction
Education for diet and exercise every 2 weeks \----------- Dietary calorie restriction: reduce their usual intake by -500kcal/day
BEHAVIORALExercise
Education for diet and exercise every 2 weeks \----------- Exercise: more than 60min/day of exercise with moderate activity level twice per day
BEHAVIORALDiet and exercise
Education for diet and exercise every 2 weeks \----------- Exercise education like as exercise group and diet education like as diet group
Sponsors
Eulji University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Type 2 diabetic patient * BMI\>23kg/m2 * Female
Exclusion criteria
* The patients with co-morbidity such as heart failure, chronic kidney disease or liver cirrhosis
Outcome results
None listed