Tryptophan Metabolism in Kidney Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00758537

Enrollment

Registered

2008-09-25

Start date

2007-01-31

Completion date

2008-10-31

Last updated

2009-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Keywords

Assessment of tryptophan and tryptophan catabolites and IDO-activity in patients with chronic kidney disease

Brief summary

Tryptophan metabolism in kidney disease will be investigated in patients with chronic kidney disease stages (ADOQI 3-5). Tryptophan levels and respective catabolites will be assessed under hemodialysis.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Chronic kidney disease (for \> 3months) stages (National Kidney foundation/ADOQI): 3-5

Exclusion criteria

* Signs of infection or systemic inflammation

Design outcomes

Primary

Measure	Time frame
Course of plasma tryptophan level and levels of tryptophan metabolites under standard low-flux hemodialysis.	does not apply

Countries

Germany

Outcome results