Gastric Cancer
Conditions
Keywords
gastric cancer, surgery, prophylactic cholecystectomy
Brief summary
The patients will be divided into two groups: in the first group the patient will be submitted to prophylactic cholecystectomy during standard surgery for curable gastric cancer (subtotal or total gastrectomy), while in the second group will be submitted to standard gastric surgery only.
Detailed description
The incidence of gallstones and gallbladder sludge is known to be higher in patients after gastrectomy than in general population. This higher incidence is probably related to surgical dissection of the vagus nerve branches and the anatomical gastrointestinal reconstruction. Therefore, some surgeons perform routine concomitant cholecystectomy during standard surgery for gastric malignancies. However, not all the patients who are diagnosed to have cholelithiasis after gastric cancer surgery will develop symptoms or require additional surgical treatments and a standard laparoscopic cholecystectomy is feasible even in those patients who underwent previous gastric surgery.
Interventions
PROCEDUREcholecystectomy
prophylactic cholecystectomy during standard gastric surgery for cancer
Sponsors
Azienda Ospedaliero-Universitaria Careggi
Italian Research Group for Gastric Cancer
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing standard gastric surgery for cancer
Exclusion criteria
* gallbladder disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduced biliary complications | 5 years |
Secondary
| Measure | Time frame |
|---|---|
| Improved quality of life | 5 years |
Countries
Italy
Outcome results
None listed