Requirement of Analgesics After Two Remifentanil Dosing Regimen in Cardiac Surgery.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00757198

Acronym

REMISYD

Enrollment

Registered

2008-09-23

Start date

2008-09-30

Completion date

2011-12-31

Last updated

2013-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

pain, postoperative, opioid, PCA, cardiac surgery

Brief summary

Prospective double blind study comparing two remifentanil dosing protocols (0.1 and 0.3 mcg/kg/min) during cardiac surgery. Main outcome measures are postoperative opioid requirements (PCA oxycodone) and postoperative pain (VAS, verbal rating scale).

Interventions

DRUGremifentanil

remifentanil infusion

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Coronary artery bypass grafting patients

Exclusion criteria

* Psychiatric disorders, sleep apnea, cardiac insufficiency

Design outcomes

Primary

Measure	Time frame
Postoperative opioid (oxycodone) consumption	Postoperatively 48 hours

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026