The Evolution and Management of Migraine Recurrence Beyond 24 Hours

The Evolution and Management of Migraine Recurrence Beyond 24 Hours: A Prospective Study of Tertiary Care Center Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00754611

Enrollment

100

Registered

2008-09-18

Start date

2008-12-31

Completion date

2010-12-31

Last updated

2019-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Brief summary

What is the course of migraine headache recurrence, how is it managed, what characteristics are associated with it, and how does it influence patient satisfaction with treatment?

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Female and male patients at University Headache Center with \> 6 month diagnosis of migraine with and/or without aura (ICHD-II) * Greater than or equal to 18 years old

Exclusion criteria

* Greater than 15 days/month total headache days * Analgesic use greater than 15 days/month (other than aspirin less than or equal to 325mg/d)

Design outcomes

Primary

Measure	Time frame
Primary efficacy outcomes will be sustained pain free response between 4 and 72 hours after initial abortive medication dosing (lack of recurrence over 72 hours)	4 to 72 hours

Secondary

Measure	Time frame
Pain response and pain free data	30 minutes, 1,2,4,24,48,and 72 hours
Rate of recurrence, time of recurrence, time to re-dosing	72 hours
Rate of recurrence among multiple attacks per subject	72 hours

Countries

United States

Outcome results