Subcuticular Suture Versus Synthetic Glue in Thyroidectomy Incision

Comparison of Esthetic Results Between Subcuticular Suture and Synthetic Glue in Thyroidectomy Incision: a RCT

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00754182

Acronym

SCSvsSG

Enrollment

100

Registered

2008-09-17

Start date

2008-09-30

Completion date

2010-05-31

Last updated

2010-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Goiter, Parathyroid Pathologies, Thyroid Neoplasms

Keywords

thyroidectomy, surgery, synthetic glue, subcuticular suture

Brief summary

The aim of this study is to compare aesthetic results of two different type of sutures (subcuticular versus synthetic glue) in post-thyroidectomy incisions. It is a randomized clinical trial (single blinded) designed as a superiority study, since in the authors' hypotheses glue can give better results compared with subcuticular suture in this particular district. Secondary objective is to investigate if other factors (like the use of cold/warm blade, the sex, the presence of diabetes, the lenght of incision) can influence aesthetic results.

Interventions

DEVICEOctylcyanoacrylate (Dermabond)

Synthetic glue for surgical use (skin closure)

DEVICESubcuticular reabsorbable suture (Caprosyn)

Every stitch is positioned in the subcuticular tissue by a continuous technique

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients underwent thyroidectomy, emithyroidectomy, parathyroidectomy

Exclusion criteria

* Former neck operations with external incisions * Post-operative bleeding * Cervical nodes involvement (with the necessity of widened incisions)

Design outcomes

Primary

Measure	Time frame
Scar evaluation scale for short term esthetic results (Hollander, J. E., Singer, A. J., Valentine, S., and Henry, M. C. Wound registry: Development and validation. Ann. Emerg. Med. 25: 675, 1995.)	10 days

Secondary

Measure	Time frame
Scar Evaluation Scale (by Adam J. Singer, M.D. et al. Development and Validation of a Novel Scar Evaluation Scale Plastic and Reconstructive Surgery ,December 2007 Volume 120, Number 7 ,1892-1897)	3 months

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026