Acute Myocardial Infarction
Conditions
Keywords
AMI,, Reperfusion, successful
Brief summary
The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).
Detailed description
CMR was performed in 38 consecutive patients with AMI 3±1 days after successful reperfusion using a clinical 1.5 Tesla MR-scanner. Ten healthy volunteers served as controls. SENC is a technique that directly measures peak circumferential strain from long-axis views and peak longitudinal strain from short axis views. Measurements were obtained for each segment in a modified 17 segment model. Wall motion and infarcted tissue were evaluated semi-quantitatively from SSFP cine sequences and contrast-enhanced-MR-images and were then related to myocardial strain. Comparison of peak circumferential strain assessed by SENC and MR-tagging was performed.
Interventions
PROCEDUREcardiac MRI
cardiac MRI at one time point for group 1 after intervention for group 2 at any time point
Sponsors
Heidelberg University
RWTH Aachen University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with AMI after successful reperfusion * Healthy volunteers in control group
Exclusion criteria
* No reperfusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular function | 01.01.2007 until 01.02.2007 |
Secondary
| Measure | Time frame |
|---|---|
| Transmurality | 01.01.2007 until 01.02.2007 |
Countries
Germany
Outcome results
None listed