Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00749983

Enrollment

Registered

2008-09-10

Start date

2009-06-30

Completion date

2012-07-31

Last updated

2012-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis, Fibromyalgia

Brief summary

The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.

Interventions

DIETARY_SUPPLEMENTCreatine supplementation

DIETARY_SUPPLEMENTDextrose supplementation

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Fulfill ACR criteria of knee osteoarthritis * Fulfill ACR criteria of fibromyalgia

Exclusion criteria

* Athletes * Drugs stable for at least three months before entering the study * No limitations to resistance training

Design outcomes

Primary

Measure	Time frame	Description
Physical function	12 weeks	Assessed by the timed-stands test

Secondary

Measure	Time frame	Description
Strength	12 weeks	Assessed by the 1-repetition maximum test
Quality of life	12 weeks	health-related questionaires
Body composition	12 weeks	Assessed by DXA
Renal function	12 weeks	Assessed by 51Cr-EDTA

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026