Radical Perineal Prostatectomy
Conditions
Keywords
capsular incision, biochemical recurrence, radical perineal prostatectomy
Brief summary
To evaluate the impact of capsular incisions on biochemical recurrence (BCR) and the potential risk factors of capsular incisions.
Detailed description
The pathological classification of the prostate following radical prostatectomy provides important prognostic information; an accurate pathology report is the cornerstone to cancer treatment and follow-up. In addition to the preoperative serum PSA, Gleason score on pathology specimens, seminal vesicle invasion and lymph node status, and a positive surgical margin with extraprostatic extension (EPE) are significant predictors of clinical and biochemical recurrence. However, the prognostic implication of a capsular incision, a tumor extending to the inked margins without a histologically documented EPE, remains to be defined.
Interventions
None listed
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
43 Years to 78 Years
Healthy volunteers
No
Inclusion criteria
* pathologically proven prostate cancer * follow-up for at least 6 months
Exclusion criteria
* insufficient biopsy data * seminal vesicle invasion or lymph node involvement on pathology * neoadjuvant or adjuvant therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biochemical recurrence of prostate cancer | upto the final date of study |
Secondary
| Measure | Time frame |
|---|---|
| risk factors for capsular incisions | at surgery |
Countries
South Korea
Outcome results
None listed