Dynamic MRI of the Behaviour of Female Pelvic Floor

The Suitability of Dynamic MRI for Pelvic Floor, Bladder Neck and Midurethra

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00747370

Enrollment

Registered

2008-09-05

Start date

2002-01-31

Completion date

2008-06-30

Last updated

2008-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genital Prolapse, Stress Urinary Incontinence

Keywords

stress urinary incontinence, Tension free vaginal tape, tension free vaginal tape obturator, genital prolapse

Brief summary

The purpose of this study was to test the suitability of dynamic magnetic resonance imaging for the pelvic floor floor, bladder neck and urethra in healthy volunteers, in stress incontinent patient and in women with genital prolapse.

Detailed description

Traditional methods for evaluation of urinary incontinence in women include urodynamics, cystourethroscopy, cystourethrography and ultrasonography.Magnetic resonance imaging (MRI) offers a new tool for evaluation of morphology and function of the urogenital compartment of the female pelvis. Moreover, MRI gives opportunity to study function of the pelvic floor organs in terms of mobility and reactions during different physiological and provocative activities. The aim of the present study was by means of dynamic MRI to evaluate the behaviour of the mid-urethra, bladder neck, cervix and rectum in different maneuvers in three different study groups. Sixteen healthy volunteers with no complaints of urinary symptoms or urogenital prolapses, 42 stress urinary incontinence patients and 16 women with third degree genital prolapse were examined respectively.

Interventions

PROCEDUREmovement of midurethra, bladder neck, cervix and rectum

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* healthy women without any urogenital symptoms * stress urinary incontinence ( group II ) * genital prolapse of third degree ( group III)

Exclusion criteria

* previous incontinence or prolapse surgery * lower urinary tract anomaly * current UTI or \> 3 UTI episodes within the past year * previous radiation therapy of the pelvis * active malignancy * neurogenic disease which can be associated with bladder disorders * patient unable to understand the purpose of the study * patient immobile

Design outcomes

Primary

Measure	Time frame
The movement of midurethra, bladder neck, cervix and rectum measured by dynamic MRI	5 years

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026