Unresectable Hilar Cholangiocarcinoma
Conditions
Keywords
Hilar cholangiocarcinoma, biliary stent, plastic stent, metallic stent, quality of life
Brief summary
The purpose of this study is to compare the quality of life in patients with unresectable hilar cholangiocarcinoma on palliative metallic stent versus plastic Stent.
Detailed description
In the patient with unresectable hilar cholangiocarcinoma,palliative biliary stent is the one way to help him. The aim of palliative treatment is to improve quality of life and relief symptom,or sometime ,extended survival rate. There are two types of biliary stent: 1. plastic stent made from polyethylene or polytetrafluoroethylene 2. metalic stent braided in the form of a tubular mesh from surgical-grade stainless steel alloy and designed to expand to a maximum diameter of 10mm. The main drawback of plastic stent is relatively high occlusion rate, but its advantage is the lower cost. In the reasons of higher occlusion rate , the lower cost of plastic stent versus metallic stent that should be stent exchange when occluded, so we would to know about quality of life in both group.
Interventions
DEVICEbiliary stent
Metallic stent of plastic stent was inserted into right or left hepatic duct which was planed before intervention using CT scan or MRCP
Sponsors
Khon Kaen University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patient with diagnosis of hilar cholangiocarcinoma and/or radiological diagnosis * Patient considered having an unresectable tumor or unfit of operation because of advanced age or medical illness
Exclusion criteria
* Patient with ASA 4 or 5 * Patient who inability to comply with follow up * Patient refused to join the research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assessment of the quality of life of patient with unresectable hilar cholangiocarcinoma after palliative biliary stent. | 2-4 weeks |
Secondary
| Measure | Time frame |
|---|---|
| To assessment of early and late complication after palliative stent. | After stent insertion for sixth month and one year or until patients were expired |
| Survival rate at sixth month and one year. | After stent insertion for sixth month and one year or until patients were expired |
Countries
Thailand
Contacts
Primary ContactWorrarat Kongkasame, MD
Outcome results
None listed