Skip to content

Treat Arterial Hypertension and Diabetes in Rural Africa

A Prospective Randomised Trial Comparing Three Interventions to Improve Treatment Adherence Among Patients With Arterial Hypertension or Diabetes in Rural Cameroon (TAHADIRA-trial 1)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00744458
Acronym
TAHADIRA
Enrollment
223
Registered
2008-09-01
Start date
2008-08-31
Completion date
2010-02-28
Last updated
2010-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, Arterial Hypertension

Keywords

Primary Health care in rural Africa, Chronic non-communicable diseases, Patient Compliance, Treatment adherence

Brief summary

The purpose of this study is to determine the efficacy of three different interventions to improve treatment adherence among patients with arterial hypertension or diabetes in rural Cameroon.

Detailed description

Non communicable chronic diseases such as arterial hypertension (AH) and diabetes (DM) are a great burden for public health in Cameroon. However, outside the main cities access to appropriate diagnosis and treatment of these health-conditions is still very poor. The Swiss NGO Fondation Coopération Afrique started in 2007 a program to integrate chronic disease management with focus on AH and DM into the primary health care system of peripheral non-physician health facilities in a rural area of Central Cameroon. A first evaluation after one year revealed very low treatment adherence among the newly diagnosed patients as the main challenge. In order to improve patient's adherence we expose them randomly to one of three interventions: The first intervention consists in a written agreement on long-lasting therapy (treatment contract). Patients get information about the importance of a regular long term treatment and personal engagement to follow treatment and clinical controls regularly. The second intervention introduces in addition to the treatment contract a reminder system. In case of follow-up failure a community worker traces the patient to recall the visit at the health centre. The third intervention consists of the treatment contract combined with a financial incentive in form of one month free treatment after four months of regular follow-up. We allocated randomly one of the three interventions to each health center.

Interventions

OTHERTreatment contract

Patients signs in for a agreement - to respect a regular follow-up at the health facility.

OTHERTracing and recall at home by a community worker

The local health committee sends out a member to trace the patient and to motivate him to take up again regular treatment visits.

Incentive by giving free treatment after a 4-month regular follow-up

Sponsors

Cooperation Afrique
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with newly diagnosed arterial hypertension or non insulin dependent diabetes type 2 which require treatment and can be treated in the health centre * Informed consent by the patient

Exclusion criteria

* Patient already under treatment * Patients who need to be referred to a hospital * No informed consent by the patient

Design outcomes

Primary

MeasureTime frame
Percentage of patients with regular follow-up one year after the treatment was startedOne patient year

Secondary

MeasureTime frame
Percentage of missed control-visitsOne patient year
Treatment response of diabetic patients (fasting blood glucose)One patient year
Treatment response of patients with arterial hypertension (blood pressure)One patient year

Countries

Cameroon

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026