Impact of Maternal Supplementation With Dual Megadose of Vitamin A

Impact of Supplementation With Dual Megadose of Vitamin A in the Post-partum About Vitamin A Levels in Breast Milk, Serum Levels of Vitamin A and Iron in the Binomial Mother-son and Growth and Morbidity of Children Under 6 Months

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00742937

Enrollment

239

Registered

2008-08-28

Start date

2007-07-31

Completion date

2008-12-31

Last updated

2009-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovitaminosis, Vitamin A Deficiency

Keywords

Hypovitaminosis A

Brief summary

The purpose of this study is to evaluate the effect of maternal supplementation with 400,000 IU of oral retinol palmitate in the post-partum, the nutritional situation of the binomial mother-child, on growth and morbidity of children in breastfeeding in the first six months of life.

Detailed description

The effect will be assessed by the milk and blood.

Interventions

DIETARY_SUPPLEMENTvitamin A

second capsule 200,000 UI of retinol palmitate (vitamin A)plus vitamin E, eight days after delivery.

DIETARY_SUPPLEMENTPlacebo

second capsule with vitamin E, eight days after delivery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* Pregnant low-risk obstetric

Exclusion criteria

* Premature birth * Newborn babies with birth defects and / or other serious diseases

Design outcomes

Primary

Measure	Time frame
Seric retinol	six months

Secondary

Measure	Time frame
Morbidity and growth of the child.	six months

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 21, 2026