Pain Evaluation During Follicle Aspiration: Comparison of Two Sedation Protocols

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00742807

Enrollment

Registered

2008-08-28

Start date

2008-08-31

Completion date

2015-05-31

Last updated

2023-11-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

sensation, relief, during, surgery

Brief summary

Giving infiltration analgesia around the neck of the womb (= paracervical block, PCB) is frequently experienced as a painful procedure by women undergoing follicle aspiration. Two sedation protocols, where in the one protocol a low dose of alfentanil hydrochloride is already administered before the PCB, will be compared with each other and pain relief measured using the 'Visual Analogue Scale' and the 'Short-Form McGill Questionnaire'

Interventions

DRUGLow dose of alfentanil hydrochloride

Administration of low dose alfentanil hydrochloride before paracervical block

DRUGNormal dose of alfentanil hydrochloride

Normal dose of alfentanil hydrochloride is administered after paracervical block

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 43 Years

Healthy volunteers

Inclusion criteria

* Healthy women and female infertility patients * Between 18 and 43 years of age

Exclusion criteria

* Patients with a known allergy to alfentanil hydrochloride or comparable drugs (morphine, cocaine)

Design outcomes

Primary

Measure	Time frame
Pain relief	During and immediately after surgery

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026