General Anesthesia
Conditions
Keywords
Anesthetics, Sedatives, Analgesics
Brief summary
Unhealthy alcohol drinking is negatively influencing health of people and costing a large number of annual finance via secondhand effects. Additionally, unhealthy alcohol use covers a spectrum that is associated with varying degrees of risk to health. The investigators hypothesized that unhealthy alcohol drinking resulted in significant increase in anesthetic requirement during general anesthesia. This investigation would clarify the association between unhealthy alcohol use and the intraoperative consumption of anesthetics, and provide clinical evidence for preoperative assessment with respect to the alcohol drinking habit.
Interventions
BEHAVIORALAlcohol drinking
Never drinking of alcohol
Sponsors
Nanjing Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* ASA physical status I-II * Chinese * 19-45yr * Undergoing general anesthesia
Exclusion criteria
* A history of the use of centrally-acting drugs of any sort, chronic pain and psychiatric diseases records. * Participants younger than 18yr，older than 45yr or pregnancy was eliminated. * Those who were not willing to or could not finish the whole study at any time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthetic requirements | 10 min after completion of operation |
Secondary
| Measure | Time frame |
|---|---|
| Economic assessment | 1 day after operation |
| Odds Ratio of alcohol use and the consumption of anesthetics | 1 day after completion of study |
| Side effects | 30 min after completion of the study |
| Bispectral Index (BIS) value | 0, 5, 10, 20, 30, 45, 60, 90 min after anesthesia |
Countries
China
Outcome results
None listed