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Content, Bioavailability and Health Effects of Trace Elements and Bioactive Components in Organic Agricultural Systems

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00738166
Acronym
OrgTrace
Enrollment
18
Registered
2008-08-20
Start date
2007-10-31
Completion date
2010-12-31
Last updated
2016-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

diet, organic, health, healthy people

Brief summary

Trace elements, bioactive secondary metabolites and vitamins are among the most important quality parameters in plants. Yet, very little information is available on their content, bioavailability and health effects of organically grown plant food products. The main objective of the project is to study the impact of different agricultural management practises relevant for organic farming on the ability of cereal and vegetable crops to absorb trace elements from the soil and to synthesise bioactive compounds (secondary metabolites, antioxidant vitamins and phytates) with health promoting effects. Field experiments with a rigidly controlled design will be implemented together with state-of-the-art analytical techniques allowing solid conclusions to be drawn on the variability and optimum levels of bioactive compounds. The multitude of analytical data from plant and soil samples will be analysed by multivariate statistical methods in order to reveal differences between the cultivation systems used. Finally, the relationship between bioavailability of the nutrients studied and the elemental fingerprint of plants will be extracted by the statistical methods.

Interventions

OTHEROrganic or conventional diet

12 days on fully controlled organic 1 diet, organic 2 diet and conventional diet

OTHERDiet (organic or conventional)

organic or conventional diet

Sponsors

University of Copenhagen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy adults aged 18-45 years * BMI 20-30 kg/m2 * Non-vegetarian

Exclusion criteria

* Physical activity \> 10 h/week * Intake of dietary supplements * Regular use of drugs * Chronic diseases * Smoking * Excessive intake of alcohol

Design outcomes

Primary

MeasureTime frame
Bioavailability of trace elements and secondary metabolites3 x 12 days

Secondary

MeasureTime frame
Health factors3 x 12 days

Other

MeasureTime frame
miRNA1 year

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026