Acute Pain Episodes in Patients Under Opioid Maintenance Therapy : Clinical Management and Long Term Effects

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00738036

Enrollment

151

Registered

2008-08-20

Start date

2008-04-30

Completion date

2009-11-30

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pain

Keywords

Analgesics, Opioid, Opioid maintenance therapy, Acute pain

Brief summary

To define a rational pharmacological management of pain for the subjects under opioid maintenance therapy (methadone or buprenorphine), it is first of all necessary to estimate the efficiency of the current practices on pain management as well as their potentially noxious consequences, in particular on the long term opioid maintenance therapy. The objective of the study is to compare the efficiency of the opioid maintenance therapy according to the arisen of an acute painful phenomenon requiring an analgesic management for these patients. At first, this work will allow to determine the results on acute pain of the current practices for these patients. The comparison of the long term consequences on opioid maintenance therapy between the patients that presented an acute painful phenomenon and the control patients should help to improve acute pain management for these patients while limiting the risk of relapse in the abused consumption of psychoactive substances.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 18 or more. * Patients under opioid maintenance therapy (buprenorphine or methadone) * Patients treated by the same drug (buprenorphine or methadone) since at least 3 months

Exclusion criteria

* Refusal of the patient to take part in the study * Absence of possible follow-up

Design outcomes

Primary

Measure	Time frame
Retention rate under buprenorphine or methadone treatment defined as the percentage of patients still under treatment during the follow-up	1, 3, 6 and 12 months

Secondary

Measure	Time frame
pain, anxiety, drugs, alcohol and other substances abuse and dependence, drug prescription (included for pain treatment and opioid maintenance)	1, 3, 6 and 12 months

Countries

France

Outcome results