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Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain

Efficacy of Three Treatment Modalities for Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00736346
Acronym
MADONA
Enrollment
204
Registered
2008-08-15
Start date
2005-10-31
Completion date
2010-06-30
Last updated
2008-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety Disorder, Mental Disorder, Panic Disorder

Keywords

Panic Disorder, anxiety, chest pain, emergency department, cognitive-behavioral treatment

Brief summary

The purpose of this study is to assess the impact of three different treatment modalities on panic symptoms, quality of life and use of health services among individuals consulting an emergency department for non cardiac chest pain and having Panic Disorder.

Interventions

BEHAVIORALBrief cognitive-behavioral treatment for Panic Disorder

One two-hour session of cognitive-behavior therapy for panic disorder

BEHAVIORALCognitive-Behavior Therapy for Panic Disorder

Seven one-hour sessions of cognitive-behavior therapy for panic disorder

DRUGparoxetine

40 mg die, for 6 months

Sponsors

Canadian Institutes of Health Research (CIHR)
CollaboratorOTHER_GOV
Université du Québec a Montréal
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Aged 18 and over * Mastered oral and written French * Consulted an emergency department for chest pain with very low risk of coronary disease (normal ECG and blood tests) * Met criteria for Panic Disorder

Exclusion criteria

* Chest pain with an obvious medical origin (obvious trauma or abnormal pulmonary x-rays) * Had received cognitive-behavior therapy for Panic Disorder in the last six months * Cognitive impairment preventing the completion of psychological assessment * Past or present psychotic episode, Bipolar Disorder, or organic mental disorder * Current Abuse or Dependence Disorder * If another Mental Disorder is present, its severity was equal or inferior to the severity of Panic Disorder * Current medical condition preventing the participant from receiving pharmacological of cognitive-behavior treatment

Design outcomes

Primary

MeasureTime frame
Panic Disorder diagnosisPre and posttreatment, and 3, 6 and 12 months after treament

Secondary

MeasureTime frame
Panic symptomatology, psychological distress, quality of life, and use of health servicesPre and posttreatment, and 3, 6 and 12 months after treatment

Countries

Canada

Contacts

Primary ContactAndré Marchand, PhD
marchand.andre@uqam.ca1 (514) 987-3000
Backup ContactGeneviève Belleville, PhD
belleville.genevieve@uqam.ca

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026