Breast Cancer
Conditions
Keywords
Breast Cancer, Breast Biopsy, Reduction mammoplasty
Brief summary
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an adjunct to core needle biopsy. For the surgery part of the study, all patients scheduled to have a mastectomy or lumpectomy for the treatment of breast cancer will be asked if they would be willing to participate in this study. For the core needle biopsy part of the study, patients with a higher pre-probability of cancer (based on mammography) will be recruited to increase the number of patients with malignant lesions and enrolled in this investigation.
Interventions
Using core biopsy and reduction mammoplasty tissue
Sponsors
William Marsh Rice University
Duke University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DEVICE_FEASIBILITY
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients having a needle biopsy of a breast mass
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Optical signatures | Day of procedure (less than 10 minutes) | The primary outcome of this study is the identification of the optical signatures of normal and cancerous tissue of the breast |
Countries
United States
Outcome results
None listed