Appendicitis
Conditions
Keywords
Appendicitis, IV Contrast, Oral Contrast, CT scan
Brief summary
The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department. A secondary purpose will be to design a specific CT for appendicitis protocol at our institution at the conclusion of this study.
Interventions
OTHEROmnipaque
oral contrast for CT scan
Sponsors
WellSpan Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis
Exclusion criteria
* pregnant patients * patients with known IV dye or oral contrast allergy * patients in whom acute appendicitis is not the primary diagnosis * patients with renal insufficiency that may have significant adverse effect from IV dye
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity of IV contrast alone for a computed tomography scan for the diagnosis of appendicitis in the adult Emergency Department patient. | immediate reading + blinded reading within 48 hours |
Secondary
| Measure | Time frame |
|---|---|
| If IV contrast alone for CT scan is sensitive for the diagnosis of appendicitis in the adult Emergency department patient | immediate reading and blinded reading within 48 hours |
Outcome results
None listed