TIPS Versus Portacaval Shunt for Acute Bleeding Varices in Cirrhosis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00734227

Enrollment

153

Registered

2008-08-14

Start date

1996-07-31

Completion date

2006-07-31

Last updated

2008-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding

Keywords

Survival and control of hemorrhage

Brief summary

In unselected cirrhotic patients with acute portal hypertension-related bleeding to compare the effectiveness in control of bleeding, mortality rate, duration of life, quality of life, and economic costs of two widely used treatment measures: (1) emergency transjugular intrahepatic portal-systemic shunt (TIPS), and (2) emergency portacaval shunt.

Interventions

PROCEDUREEmergency portacaval shunt

OTHEREmergency TIPS

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All patients with UGI bleeding who are shown to have the findings of cirrhosis and esophagogastric varices or portal hypertensive gastropathy and require 2 or more units of blood transfusion will be included.

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
Survival	10 years

Secondary

Measure	Time frame
Control of bleeding and quality of life	10 years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026