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Interval Training in Young Healthy Individuals

Interval Training: Training, Detraining and Retraining; an Interventional Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00733941
Enrollment
24
Registered
2008-08-13
Start date
2008-09-30
Completion date
2009-12-31
Last updated
2015-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Test, Healthy Subjects

Keywords

Exercise test, Running, Arterial diameter, Monitoring, physiologic, Oxygen Consumption

Brief summary

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health. The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise. The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Detailed description

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week. The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Interventions

BEHAVIORALHigh frequency training

24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining

BEHAVIORALnormal frequence training

24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Sponsors

Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 27 Years
Healthy volunteers
Yes

Inclusion criteria

* BMI\<27, non-smokers, train less that 1-2 times per week, VO2max \<60 for male and \<50 for female.

Exclusion criteria

* Hypertension, diabetes and cardiovascular disease.

Design outcomes

Primary

MeasureTime frame
Oxygen uptakeBefore and after the training-, detraining- and retraining-phase

Secondary

MeasureTime frame
Cardiac function and skeletal muscle enzyme activityAfter training, detraining and retraining

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026