Cholangiocarcinoma, Hepatectomy, Surgical Treatment
Conditions
Keywords
Minor Liver Resection, Major Liver Resection, Hilar
Brief summary
The investigators conducted a prospective study to determine the safety and efficacy of minor and major hepatectomy selected by predetermined criteria in 138 patients with hilar cholangiocarcinoma. In selected patients, minor liver resection was a good treatment.
Detailed description
Objective: To determine the safety and efficacy of minor and major hepatectomy selected by predetermined criteria in patients with hilar cholangiocarcinoma (HC). Summary Background Data: For HC treated with hepatectomy, the extent of liver resection remains controversial despite extensive studies. Methods: From January 2000 to December 2007, we prospectively studied patients who received surgical treatment for HC. Of the 187 patients who were surgically treated, 138 (73.8%) underwent resection with a curative intent. Minor hepatectomy was carried out in 93 patients who had Bismuth-Corlette types I, II and III HC without hepatic artery/portal vein invasion; and major hepatectomy in 45 patients who had type III HC with hepatic artery/portal vein invasion, or type IV HC.
Interventions
PROCEDUREMinor or Major Liver Resection
Sponsors
Ministry of Health, China
Hepatic Surgery Clinical Research Centre of Hubei, China
Huazhong University of Science and Technology
Eligibility
Sex/Gender
ALL
Age
26 Years to 72 Years
Healthy volunteers
No
Inclusion criteria
* Criteria for resectability were absence of peritoneal or liver metastases, tumor extension to beyond secondary biliary branches bilaterally, tumor extension to secondary portal venous branches bilaterally
Exclusion criteria
* not in accordance with the above criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| On multivariate analysis, prognostic factors significantly impacted on long-term survival were UICC tumor stage and histopathologic grade. | — |
Outcome results
None listed