Platelet Rich Plasma (PRP) as a Treatment for ACHILLES Tendon Tears

PRP as a Treatment for ACHILLES Tendon Tears - Randomized-Double-Blind-Placebo Control Trail

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00731068

Enrollment

Registered

2008-08-08

Start date

2007-02-28

Completion date

2009-03-31

Last updated

2013-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achilles Tendon Tear

Keywords

Achilles tendon

Brief summary

To review the influence of patient derived PRGF on the healing process of Achilles tendon after a surgical correction of a complete tear.

Detailed description

Autologous platelet-rich matrices may aid in post surgical patients by promoting and accelerating tissue healing because of the release of growth factors including transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF) from platelet alpha-granules.

Interventions

BIOLOGICALPRGF

injection of 6cc into injured area of tendon

BIOLOGICALplacebo

injection of 6 cc of saline into injured area

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* A complete tear of Achilles tendon * Age 18-50 years old

Exclusion criteria

* under 18 year of age * pregnancy * physical or mental disabilities

Design outcomes

Primary

Measure	Time frame
improvement of symptoms / disease progress	1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026